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008			230511s2023 maua ob 001 0 eng
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020			_a9780262377423 _qelectronic book
020			_a026237742X _qelectronic book
020			_a9780262377430 _qelectronic book
020			_a0262377438 _qelectronic book
020			_z9780262547383 _qpaperback
020			_z0262547384
035			_a(OCoLC)1380753913 _z(OCoLC)1398567591
035		9	_a(OCLCCM-CC)1380753913
037			_a15380 _bMIT Press
037			_a9780262377423 _bMIT Press
040			_aDLC _beng _erda _cDLC _dMITPR _dOCLCF _dEBLCP _dN$T _dYDX _dOCLCO _dMTH
041			_aeng
042			_apcc
049			_aMAIN
050	0	4	_aRC455.4.G4 _bE97 2023
060		4	_aWM 140
082	0	0	_223 _a616.89
245	0	0	_aExploring and exploiting genetic risk for psychiatric disorders / _cedited by Joshua A. Gordon and Elisabeth B. Binder ; program advisory committee, Elisabeth B. Binder [and 6 others].
264		1	_aCambridge, Massachusetts : _bThe MIT Press, _c[2023]
300			_a1 online resource (xii, 327 pages) : _billustrations (chiefly color)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aStrüngmann forum reports
504			_aIncludes bibliographical references and index.
505	0		_aIntro -- Contents -- List of Contributors -- Preface -- 1: Exploring and Exploiting Genetic Risk for Psychiatric Disorders -- Gene Discovery -- 2: Delineating Additional Risk Factors -- 3: Data Collection -- 4: Environmental Risk and Gene-Environment Relationships in Psychiatric Disorders -- Understanding Rare Variation -- 5: Rare Variants -- 6: Promises and Challenges of Precision Medicine in Rare Neurodevelopmental Disorders -- 7: Experimental Model Systems for Rare and Common Variants -- Understanding Common Variation -- 8: Common Alleles
505	8		_a9: Hypotheses of How Common Variants Create Risk for Psychiatric Disorders -- 10: From Common Variant to Function -- 11: Contextualizing Convergent Common Variant Mechanisms through Systems Biology -- Clinical Considerations -- 12: Maximizing Near-Term Clinical Opportunities for Psychiatric Genetics -- 13: The Use of Polygenic Risk Scores in Clinical Psychiatry -- 14: Ethical Challenges Associated with Advances in Genetic Prediction of Neuropsychiatric Disorders -- 15: Psychiatric Genetic Counseling -- 16: Concluding Summary -- Bibliography -- Subject Index -- Strüngmann Forum Report Series
520			_a"This volume examines the state of psychiatric genetics and charts a path forward for further discovery and translation"-- _cProvided by publisher.
540			_aCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 International _f CC BY-NC-ND 4.0 _uhttps://creativecommons.org/licenses/BY-NC-ND/4.0/
588			_aDescription based on online resource; title from digital title page (viewed on October 09, 2023).
650		0	_aMental illness _xGenetic aspects. _0http://id.loc.gov/authorities/subjects/sh85083647
650		2	_aMental Disorders _xgenetics _0https://id.nlm.nih.gov/mesh/D001523Q000235
653			_aMEDICAL / Mental Health
653			_aMEDICAL / Psychiatry / General
653			_aPSYCHOLOGY / Psychopathology / General
655		4	_aelectronic book.
700	1		_aGordon, Joshua A., _eeditor. _0http://id.loc.gov/authorities/names/n2016186652
700	1		_aBinder, Elisabeth _q(Elisabeth B.), _eeditor. _0http://id.loc.gov/authorities/names/n2014184069
830		0	_aStrüngmann Forum reports. _0http://id.loc.gov/authorities/names/n2008180042
856	4	0	_uhttps://directory.doabooks.org/handle/20.500.12854/146733 _yFull text is available at the Directory of Open Access Books. Click here to view.
942			_2ddc _cOA