000 05145cam a2200529Ii 4500
001 968151085
003 OCoLC
005 20250319085431.0
006 m o d
007 cr cnu|||unuuu
008 170111s2017 gw m ob u001 0 eng d
020 _a9783527800599
_q(electronic bk.)
020 _a352780059X
_q(electronic bk.)
020 _a9783527800605
_q(electronic bk.)
020 _a3527800603
_q(electronic bk.)
020 _z9783527340750
_q(print)
035 _a(OCoLC)968151085
040 _aN$T
_beng
_erda
_epn
_cN$T
_dEBLCP
_dDG1
_dN$T
_dIDEBK
_dOCLCF
_dUPM
_dMERUC
_dDEBSZ
_dXPJ
_dLIP
_dOTZ
_dOCLCQ
050 4 _aTA164
072 7 _aSCI
_x013060
_2bisacsh
072 7 _aTEC
_x009010
_2bisacsh
082 0 4 _a660.6
_223
245 0 0 _aApplied bioengineering :
_binnovations and future directions /
_cedited by Toshiomi Yoshida.
264 1 _aWeinheim, Germany :
_bWiley-VCH,
_c2017.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent.
337 _acomputer
_bc
_2rdamedia.
338 _aonline resource
_bcr
_2rdacarrier.
340 _gpolychrome
_2rdacc
_0http://rdaregistry.info/termList/RDAColourContent/1003.
505 0 _aCover; Title Page; Copyright; Contents; List of Contributors; Chapter 1 Introduction; 1.1 Introduction; 1.2 Enzyme Technology; 1.3 Microbial Process Engineering; 1.3.1 Bioreactor Development; 1.3.2 Measurement and Monitoring; 1.3.3 Modeling and Control; 1.3.4 Solid-State Fermentation; 1.4 Plant Cell Culture; 1.5 Animal Cell Culture; 1.6 Environmental Bioengineering; 1.7 Composition of the Volume; References; Part I Enzyme Technology; Chapter 2 Enzyme Technology: History and Current Trends; 2.1 The Early Period up to 1890; 2.1.1 Observations and Empirical Results; 2.1.2 Theoretical Approaches.
505 8 _a2.2 The Period from 1890 to 19402.2.1 Scientific Progress; 2.2.2 Theoretical Developments; 2.2.3 Technological Developments; 2.3 A New Biocatalyst Concept -- Immobilized Enzymes; 2.3.1 Fundamental Research; 2.3.2 Examples of Industrial Development: The Case of Penicillin Amidase (PA) -- Penicillin Hydrolysis and Derivatives; 2.3.3 Examples of Industrial Development: The Case of Sugar Isomerization; 2.4 Expanding Enzyme Application after the 1950s; 2.5 Recombinant Technology -- A New Era in Biocatalysis and Enzyme Technology; 2.5.1 New Enzymes -- A Key to Genetic Engineering.
505 8 _a2.5.2 Analytical and Diagnostic Enzymes2.5.3 Expanding Market of Industrial Enzymes; 2.6 Current Strategies for Biocatalyst Search and Tailor Design; 2.6.1 Enzyme Discovery from the Metagenome or Protein Databases; 2.6.2 Protein Engineering of Enzymes; 2.6.3 Enzyme Cascade Reactions; 2.6.4 Metabolic Engineering; 2.7 Summary and Conclusions; Acknowledgment; Abbreviations; References; Chapter 3 Molecular Engineering of Enzymes; 3.1 Introduction; 3.2 Protein Engineering: An Expanding Toolbox; 3.2.1 From Sequence to Fold and Function.
505 8 _a3.2.2 Improving Enzyme Properties by Rational Design and Directed Evolution3.2.3 Designing Smart Libraries; 3.2.4 In Vivo Continuous Directed Evolution; 3.2.5 Diversification of Enzyme Functionalities by Recombination; 3.3 High-Throughput Screening Systems; 3.4 Engineered Enzymes for Improved Stability and Asymmetric Catalysis; 3.4.1 Stability; 3.4.1.1 Cellulases; 3.4.1.2 Lipases; 3.4.2 Asymmetric Biocatalysis; 3.5 De Novo Design of Catalysts: Novel Activities within Common Scaffolds; 3.6 Conclusions; References; Chapter 4 Biocatalytic Process Development.
505 8 _a4.1 A Structured Approach to Biocatalytic Process Development4.2 Process Metrics; 4.2.1 Reaction Yield; 4.2.2 Productivity; 4.2.3 Biocatalyst Yield; 4.2.4 Product Concentration; 4.3 Technologies for Implementation of Biocatalytic Processes; 4.3.1 Biocatalyst Engineering; 4.3.1.1 Protein and Genetic Engineering; 4.3.1.2 Biocatalyst Immobilization; 4.3.2 Reaction Engineering; 4.3.2.1 Reactant Supply; 4.3.2.2 Product Removal; 4.3.2.3 Two-Phase Systems; 4.4 Industrial Development Examples; 4.4.1 Development of a Biocatalytic Route to Atorvastatin (Developed by Codexis Inc., USA)
504 _aIncludes bibliographical references and index.
506 _aAvailable to OhioLINK libraries.
650 0 _aBioengineering.
_0http://id.loc.gov/authorities/subjects/sh85014134.
650 0 _aSynthetic biology.
_0http://id.loc.gov/authorities/subjects/sh2010006918.
655 4 _aElectronic books.
700 1 _aYoshida, T.
_q(Toshiomi),
_d1939-
_0http://id.loc.gov/authorities/names/n93015421
_eeditor.
710 2 _aOhio Library and Information Network.
_0http://id.loc.gov/authorities/names/no95058981.
856 4 0 _3OhioLINK
_zConnect to resource
_uhttps://rave.ohiolink.edu/ebooks/ebc2/9783527800599
856 4 0 _3Wiley Online Library
_zConnect to resource
_uhttps://onlinelibrary.wiley.com/doi/book/10.1002/9783527800599
856 4 0 _3Wiley Online Library
_zConnect to resource (off-campus)
_uhttps://go.ohiolink.edu/goto?url=https://onlinelibrary.wiley.com/doi/book/10.1002/9783527800599
913 _aN
989 7 _aapplied_bioengineering_innovations_and_futuredirections__________2017_______wia_______________________________
999 _c89828
_d89828