TY  - BOOK
AU  - Kirkiacharian,Serge
AU  - Dumond,Julien
TI  - Enzymes and drugs
T2  - Chemistry series
SN  - 9781786309396 
AV  - QP601 .K57 2024
U1  - 572/.7 23/eng/20240618
PY  - 2024///
CY  - London, UK, Hoboken, NJ
PB  - ISTE Ltd, John Wiley & Sons, Inc.
KW  - Enzymes
KW  - Electronic books
N2  - Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances
UR  - https://onlinelibrary.wiley.com/doi/book/10.1002/9781394299096
ER  -