Understanding atrial fibrillation / Peter Spector.
By: Spector, Peter [author.]
Language: English Publisher: Hoboken, NJ : Wiley-Blackwell, 2020Description: 1 online resourceContent type: text, . Media type: computer Carrier type: online resourceISBN: 9781119524601; 9781119524618 (Adobe PDF); 9781119524625 (ePub)Subject(s): Atrial Fibrillation -- physiopathology | Atrial Fibrillation -- diagnosis | Electrophysiologic Techniques, Cardiac -- methods | Cardiac Electrophysiology -- methods | Models, CardiovascularGenre/Form: Electronic books.DDC classification: 616.1/28 LOC classification: RC685.A72Online resources: Full text is available at Wiley Online Library Click here to viewItem type | Current location | Home library | Call number | Status | Date due | Barcode | Item holds |
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COLLEGE LIBRARY | COLLEGE LIBRARY | 616.128 Un22 2019 (Browse shelf) | Available | CL-53052 |
ABOUT THE AUTHOR
Peter Spector, MD, is Professor of Medicine, Professor of Electrical and Biomedical Engineering, and Director of Cardiac Electrophysiology and the Cardiac Electrophysiology Laboratory at the University of Vermont Medical Center, Burlington, VT, USA.
Includes bibliographical references and index.
TABLE OF CONTENTS
Preface ix
Acknowledgments xiii
Part I: Building blocks of fibrillation 1
Excitation and propagation 1
Source-sink relationships 2
What determines source-sink balance? 3
Propagation and reentry 4
Requirements for reentry 4
What makes a circuit? 6
Source-sink balance and rotors 6
Wave length 8
Wave length, path length, and reentry 9
Restitution 10
Initiating reentry 11
Part II: Atrial fibrillation mechanisms 21
The evolution of current concepts 21
The mass hypothesis of atrial fibrillation 30
Principles of propagation: Implications for fibrillation 32
Focal rotors 52
Micro‐reentry 55
Fibrillatory conduction or multi‐wavelet reentry? 66
Location of atrial fibrillation drivers 76
Principles of propagation: Driver interactions in fibrillation 87
Part III: Working with incomplete information 93
Cardiac mapping 93
Sample density and atrial fibrillation 115
What should we do with the patient who comes to the lab tomorrow? Putting it all together (without “it all”) 128
Putting it all together: Atrial fibrillation in three questions 132
Appendix A: Calculating probability in a random walk 135
Appendix B: Dominant frequency analysis 137
Appendix C: A stupid idea, but a learning opportunity 143
References 149
Index 161
"Physicians today are being presented with voluminous and conflicting information about the mechanisms responsible for AF, the tools to identify its drivers and the strategies appropriate for its treatment. This book is meant to provide physicians with the information and analytic tools required interpret the studies that purport to solve the AF puzzle. The aim of the book is to 1) explain the mechanisms responsible for initiating and perpetuating AF by building from fundamental electrophysiologic principles, 2) review the experimental data that has shaped our current understanding of AF, 3) describe the analytic methods used to interpret the experimental data, 4) explore the implications that the above information has with regard to mapping and ablation of AF. The book will be written from first principles, it is designed for readers with a foundation in electrophysiology. The intended audience is physicians, fellows, residents, electrophysiology lab staff and industry personnel interested in treating atrial fibrillation"--Provided by publisher.
Description based on print version record and CIP data provided by publisher.
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