Randomised clinical trials : (Record no. 92092)

000 -LEADER
fixed length control field 11909cam a2200601 i 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250826085106.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cnu---unuuu
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250826s2021 njum ob u001 0 eng
016 ## - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER
Record control number
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781119524649
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781119524656
Qualifying information electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1119524652
Qualifying information electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781119524687
Qualifying information electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1119524687
Qualifying information electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781119524670
Qualifying information electronic publication
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1119524679
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9781119524649
Qualifying information paperback
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1002/9781119524687
Source of number or code doi
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)1198988697
Canceled/invalid control number (OCoLC)1254088976
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
042 ## - AUTHENTICATION CODE
Authentication code pcc
050 04 - LIBRARY OF CONGRESS CALL NUMBER
Classification number R853.C55
Item number M337 2021
060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number W 20.55.C5
082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610.72/4
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Preferred name for the person Machin, David,
Dates associated with a name 1939-
Authority record control number http://id.loc.gov/authorities/names/no2006063962
Relator term author.
245 10 - TITLE STATEMENT
Title Randomised clinical trials :
Remainder of title design, practice and reporting /
Statement of responsibility, etc David Machin, Peter M. Fayers, Bee Choo Tai.
250 ## - EDITION STATEMENT
Edition statement Second edition.
264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Hoboken, NJ :
Name of publisher, distributor, etc Wiley Blackwell,
Date of publication, distribution, etc 2021.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (xiv, 536 pages)
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent.
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia.
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier.
340 ## - PHYSICAL MEDIUM
Source rdacc
Authority record control number or standard number http://rdaregistry.info/termList/RDAColourContent/1003.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
520 ## - SUMMARY, ETC.
Summary, etc "It is now more than ten years since the first edition of this book was published. In the intervening years, while many things have remained unchanged, there have also been many new developments over the period. This second edition refreshes the first, refining some of the sections to better explain their contents and, at the same time, replacing some examples with more current illustrations. To reflect the changes, we have created new chapters by splitting and then expanding old chapters. Thus, we now include full chapters on data and safety monitoring including interim analyses of accumulating data, cluster designs, repeated measures, and non-inferiority designs as there has been a rapid increase in the use of such trial designs along with some methodological developments and improvements in statistical software available for analysis. In addition, we have included entirely new chapters on stepped wedge designs, genomic targets and, feasibility and pilot studies. The chapter on stepped wedge designs reflects the growing importance of such complex intervention designs while that on genomic targets highlights the research focus directed towards more individualised medicine. In contrast the new chapter concerned with feasibility and pilot studies brings us back to the early planning stages of the clinical trial which is planned. The chapter is included as there is increasing recognition that perhaps a more structured approach is required at the planning stage of any proposed trial. The intention is to help avoid the conduct of clinical trials which fail due to the basic assumptions made at the planning stage being inappropriate. This edition is divided into three sections: I Basic Considerations, II Adaptions of the Basic Design, and III Further Topics. As the title suggests, the first section is intended to cover topics that are relevant to all randomised trials of whatever design and complexity. Thus, it may be the key section for those who are new to clinical trials and an aide-memoire for those more experienced in this area. For this purpose, it concentrates on the parallel two-group controlled trial with a single outcome measure where patients are randomised individually to one of the two interventions concerned. The second section expands on the individually randomised design in several ways by considering paired designs, repeated assessments of the (same) outcome measure over time, more than two interventions, and non-inferiority trials. It also includes cluster trials, and stepped wedge designs in which groups rather than individuals are randomised to the interventions concerned. The final section deals with genomic targets, feasibility and pilot studies, and a final chapter on miscellaneous topics including adaptive designs, large simple trials and very small trials with new additions describing alpha spending functions and the predictive probability test for use in interim analyses"--
Assigning source Provided by publisher.
545 0# - BIOGRAPHICAL OR HISTORICAL DATA
Biographical or historical note About the Author<br/>David Machin, Leicester Cancer Research Group, University of Leicester, UK; and Medical Statistics Group, School of Health and Related Research, University of Sheffield, UK.<br/><br/>Peter M. Fayers, Institute of Applied Health, University of Aberdeen, UK.<br/><br/>Bee Choo Tai, Saw Swee Hock School of Public Health, National University of Singapore, and National University Health System, Singapore; and Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Clinical trials.
Authority record control number http://id.loc.gov/authorities/subjects/sh85027069.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Clinical trials
Authority record control number http://id.loc.gov/authorities/subjects/sh85027069
General subdivision Methodology.
Authority record control number http://id.loc.gov/authorities/subjects/sh99001902.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Clinical trials
Authority record control number http://id.loc.gov/authorities/subjects/sh85027069
General subdivision Evaluation.
Authority record control number http://id.loc.gov/authorities/subjects/sh00005674.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Clinical trials
General subdivision Statistical methods.
Authority record control number http://id.loc.gov/authorities/subjects/sh2009120433.
650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Randomized Controlled Trials as Topic
General subdivision methods.
Authority record control number https://id.nlm.nih.gov/mesh/D016032Q000379.
650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedical Research
General subdivision methods.
Authority record control number https://id.nlm.nih.gov/mesh/D035843Q000379.
650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Research Design.
Authority record control number https://id.nlm.nih.gov/mesh/D012107.
650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Data Interpretation, Statistical.
Authority record control number https://id.nlm.nih.gov/mesh/D003627.
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Fayers, Peter M.,
Authority record control number http://id.loc.gov/authorities/names/n97802773
Relator term author.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Tai, Bee Choo,
Authority record control number http://id.loc.gov/authorities/names/n2013183324
Relator term author.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://onlinelibrary.wiley.com/doi/book/10.1002/9781119524687
Link text Full text is available at Wiley Online Library Click here to view
942 ## - ADDED ENTRY ELEMENTS
Source of classification or shelving scheme
Item type EBOOK
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Source of acquisition Full call number Date last seen Price effective from Item type
          COLLEGE LIBRARY COLLEGE LIBRARY 2025-08-26 ALBASA Consortium 610.724 M1842 2021 2025-08-26 2025-08-26 EBOOK