Looking at ribozymes : (Record no. 90990)

000 -LEADER
fixed length control field 05144nam a2200469 i 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250705100755.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cnu|||unuuu
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250705s2023 enkm ob u001 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781786309778
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781394276639
Qualifying information (electronic bk. : oBook)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 139427663X
Qualifying information (electronic bk. : oBook)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9781786309778
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1002/9781394276639
Source of number or code doi
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)1425166238
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QP623.5.C36
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 049000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 045000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code PN
Source bicssc
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.8/8
Edition number 23/eng/20240306
100 1# - MAIN ENTRY--PERSONAL NAME
Preferred name for the person Masquida, Benoit,
Relator term author.
245 10 - TITLE STATEMENT
Title Looking at ribozymes :
Remainder of title biology of catalytic RNA /
Statement of responsibility, etc Benoit Masquida.
264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc London, UK :
Name of publisher, distributor, etc ISTE Ltd. ;
Place of publication, distribution, etc Hoboken, NJ :
Name of publisher, distributor, etc Wiley,
Date of publication, distribution, etc ©2024.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (192 pages)
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent.
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia.
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier.
340 ## - PHYSICAL MEDIUM
Source rdacc
Authority record control number or standard number http://rdaregistry.info/termList/RDAColourContent/1003.
490 1# - SERIES STATEMENT
Series statement Biology series. Nucleic acids set ;
Volume number/sequential designation volume 2.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - CONTENTS
Formatted contents note Table of Contents<br/>Foreword vii<br/><br/>Preface xi<br/><br/>Chapter 1 Fundamentals of RNA and Ribozyme Structure 1<br/><br/>1.1 Sequences and secondary structures 2<br/><br/>1.2 RNA folding, tertiary structures and 3D 8<br/><br/>1.2.1 Secondary structures and RNA folding 8<br/><br/>1.2.2 The pseudoknot 12<br/><br/>1.2.3 The loop E 14<br/><br/>1.2.4 The k-turn 16<br/><br/>1.2.5 Tetra-loop receptors 18<br/><br/>1.2.6 The A-minor pattern 20<br/><br/>1.2.7 Comparative analysis of sequences 24<br/><br/>Chapter 2 Ribozymes and the "Central Dogma" of Molecular Biology 29<br/><br/>2.1 The discovery of RNA catalysis and the central dogma of molecular biology 29<br/><br/>2.2 In search of the primordial polymerase 34<br/><br/>Chapter 3 The Discovery of Ribozymes 37<br/><br/>3.1 The discovery of catalysis by autocatalytic introns 38<br/><br/>3.2 The discovery of RNA catalysis of RNase P 42<br/><br/>3.3 The first consequences of these discoveries 46<br/><br/>3.3.1 The ribosome, a long-ignored ribozyme 47<br/><br/>3.3.2 The modified bases 52<br/><br/>3.4 The spliceosome, another ribozyme 55<br/><br/>3.4.1 Nucleolytic ribozymes 56<br/><br/>Chapter 4 Ribozyme Engineering and the RNA World 73<br/><br/>4.1 Classification of ribozymes 75<br/><br/>4.2 Classification of ribozymes according to catalytic mechanism 76<br/><br/>Chapter 5 Structures of Ribozymes 81<br/><br/>5.1 Structures and catalytic mechanisms of ribozymes 81<br/><br/>5.1.1 Hammerhead ribozymes 81<br/><br/>5.1.2 The example of the hairpin ribozyme 87<br/><br/>5.1.3 The example of the glmS ribozyme 89<br/><br/>5.2 An example of catalysis control: lariat-capping ribozyme 91<br/><br/>Chapter 6 Evolution of the Vision of the Catalytic Mechanisms of Ribozymes, the Hammerhead Ribozyme 99<br/><br/>6.1 Chemistry and catalysis: between general acid/base and metal cations 99<br/><br/>6.2 Difficulties in interpreting catalysis data 103<br/><br/>Chapter 7 The Distribution of Ribozymes in Living Organisms and Molecular Adaptations during Evolution 111<br/><br/>7.1 Ubiquitous ribozymes 111<br/><br/>7.2 Selection pressures at work in ribozyme shaping 113<br/><br/>7.3 Ribozymes in cellular processes: from viroids to eukaryotes 117<br/><br/>7.4 Very human ribozymes 123<br/><br/>Conclusion 133<br/><br/>References 135<br/><br/>Index 165
520 ## - SUMMARY, ETC.
Summary, etc Behind the neologism "ribozymes" lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome. At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly "proteocentric" vision, inherited from the dogma of molecular biology, to a more "nucleocentric" one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious. Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.
545 0# - BIOGRAPHICAL OR HISTORICAL DATA
Biographical or historical note About the Authors<br/>Benoît Masquida is director of research at the French National Center for Scientific Research (CNRS) and carries out his research and teaching activities at the University of Strasbourg, France. He is the author of over 60 publications and is one of France’s leading specialists in ribozymes.<br/><br/>Fabrice Leclerc is a research fellow at the CNRS and conducts his research at the Paris-Saclay University, France. He has published numerous articles on RNA catalysis in ribozymes and their role in viroids and in the RNA world.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Catalytic RNA.
Authority record control number https://id.loc.gov/authorities/subjects/sh89006601.
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Leclerc, Fabrice,
Relator term contributor.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Biology series. Nucleic acids set ;
Volume number/sequential designation volume 2.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://onlinelibrary.wiley.com/doi/book/10.1002/9781394276639
Link text Full text is available at Wiley Online Library Click here to view
942 ## - ADDED ENTRY ELEMENTS
Source of classification or shelving scheme
Item type EBOOK
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Source of acquisition Full call number Date last seen Price effective from Item type
          COLLEGE LIBRARY COLLEGE LIBRARY 2025-07-05 ALBASA Consortium 572.8/8 2025-07-05 2025-07-05 EBOOK